Toxin AdTx1
UniProtKB accession: P85092
Grouped By: Matching UniProtKB accession
Group Content:
Go to UniProtKB: P85092
UniProtKB description: Orthosteric antagonist of the alpha-1A adrenergic receptor (ADRA1A) with an affinity of 0.35 nM (PubMed:20015090). Has also affinity for ADRA1B > ADRA2C > ADRA1D (PubMed:23935897). Acts as a relaxant of smooth muscle. Reduces prostatic muscle tone as efficiently as tamsulosin (an antagonist presently used), but with fewer cardiovascular side effects (PubMed:23005263).
Group Members:
Release Date:
Structure Features
Sequence Features
Experimental Features
Organisms
Protein Domains
Function
