Iron-sulfur cluster assembly protein SufA

UniProtKB accession:  P77667

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Member of gene cluster sufABCDSE that mediates iron-sulfur cluster assembly under oxidative stress and iron limitation conditions (PubMed:17941825). Binds [2Fe-2S] and [4Fe-4S] clusters by mobilizing sulfur atoms provided by the SufS-SufE cysteine desulfurase system and then transfers the assembled Fe-S clusters to target proteins including ferredoxin and aconitase (PubMed:17350000, PubMed:19366265). Seems to act as a Fe-S cluster carrier rather than a scaffold, this role being performed by SufB and SufC (PubMed:19810706, PubMed:23018275).