tRNA(Met) cytidine acetyltransferase TmcA

UniProtKB accession:  P76562

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). It recognizes the wobble base of tRNA(Met), thus distinguishing between tRNA(Met) and the structurally similar tRNA(Ile2) (PubMed:18668122, PubMed:19322199). Could use an RNA helicase motor driven by ATP hydrolysis to deliver the wobble base of tRNA(Met) to the acetyltransferase domain of TmcA (Probable).