Acetate CoA-transferase subunit alpha

UniProtKB accession:  P76458

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UniProtKB description:  Coenzyme A transferase which is involved in short-chain fatty acid degradation and catalyzes the activation of short-chain fatty acids to their respective CoA thiolesters (PubMed:1103739, PubMed:3025185). During acetoacetate degradation, catalyzes the transfer of CoA from acetyl-CoA to acetoacetate by a mechanism involving a covalent enzyme-CoA compound as a reaction intermediate (PubMed:1103741). Utilizes a variety of short chain acyl-CoA and carboxylic acid substrates but exhibits maximal activity with normal and 3-keto substrates (PubMed:1103739).