LIM domain-binding protein 1
UniProtKB accession: P70662
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Go to UniProtKB: P70662
UniProtKB description: Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors (PubMed:8918878, PubMed:9192866). May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions (PubMed:8918878, PubMed:9315627, PubMed:9192866, PubMed:16815859, PubMed:18539116). Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1 (PubMed:12150931, PubMed:8876198, PubMed:18539116). Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression (PubMed:8918878). Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (PubMed:9391090).
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