Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
UniProtKB accession: P63151
Grouped By: Matching UniProtKB accession
Group Content:
Go to UniProtKB: P63151
UniProtKB description: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Essential for serine/threonine-protein phosphatase 2A-mediated dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint (PubMed:33108758).
Group Members:
Release Date:
Structure Features
Sequence Features
Experimental Features
Organisms
Protein Domains
Function