Sirohydrochlorin cobaltochelatase

UniProtKB accession:  P61816

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis (PubMed:12686546). Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation (PubMed:28225763). Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni-sirohydrochlorin (PubMed:28225763).