Potassium channel toxin gamma-KTx 2.2

UniProtKB accession:  P59938

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Blocks human and/or rat Kv11.1/KCNH2/ERG1, Kv11.2/KCNH6/ERG2 and Kv11.3/KCNH7/ERG3 by binding to channel outer vestibule (S5P domain) with a 1:1 stoichiometry (By similarity). Has also a minimal effect on rat ELK1/KCNH4 potassium channels (By similarity). Has been shown to weakly inhibit Kv11.1/KCNH2/ERG1, Kv1.1/KCNA1, Kv1.2/KCNA2 and Kv1.3/KCNA3 voltage-gated potassium channels (PubMed:29483648).