Tubulin beta-2 chain

UniProtKB accession:  P52275

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (By similarity). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms (By similarity). Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (By similarity). Required for the normal dynamic behavior of the non-centrosomal microtubules in the epidermal syncytium (PubMed:31995031). Involved in the redistribution of microtubule end-binding protein EB1/ebp-2 caused by wounding (PubMed:31995031). Required to modulate expression in the epidermis of antimicrobial peptides, such as nlp-29, after wounding, or fungal infection (PubMed:31995031).