Potassium channel toxin alpha-KTx 3.2

UniProtKB accession:  P46111

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Potent inhibitor of the Shaker potassium channels and its mammalian homologs (Kv1.1/KCNA1, Kv1.3/KCNA3, Kv1.6/KCNA6) (Ki<1 nM for all channels) (PubMed:8204618, PubMed:20007782). Also blocks Kv1.2/KCNA2 (IC(50)=26.8 nM) (PubMed:8204618, PubMed:20007782). It also shows a weak interaction with nicotinic acetylcholine receptors (nAChR), suggesting it may weakly inhibit it (PubMed:31276191).