Phragmoplastin DRP1A

UniProtKB accession:  P42697

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Microtubule-associated force-producing protein that is targeted to at the leading edges of the forming cell plate during cytokinesis (PubMed:18612642). Also plays a major role in plasma membrane maintenance and cell wall integrity with implications in vesicular trafficking, polar cell expansion, vascular formation, and other aspects of plant growth and development, including stigmatic papillae expansion (PubMed:18256049, PubMed:18344418). Collaboratively with DRP2B, participates in clathrin-coated vesicle formation during endocytosis (PubMed:20231465). Necessary for BOR1 polar localization in low-boron (B) conditions as well as for BOR1 endocytosis and subsequent degradation under high-concentration of boron (PubMed:27449211). Has a GTPase activity (PubMed:20171176). Required for the sterols-dependent dynamic high lipid order observed at the cell plate of dividing cells (PubMed:25234576). Together with SH3P2, converts the fused vesicles to tubular structures at the cell plate and phragmoplasts during cytokinesis (PubMed:28584166, PubMed:18256049). With DRP2B and PIP5K3, required for the precise coordination of polar ARAC3/ROP6 and ARAC4/ROP2 placement and subsequent root hair positioning during planar polarity formation in root hair-forming cells, probably by mediating the correct basal-to-planar polarity switching of D6PK into the polar, lipid-enriched domain (PubMed:27251533). Involved in endocytosis required for cellulose deposition during cell wall formation and elongation (PubMed:18256049). Interacts with plasma membrane-mimetic liposomes and induces their clustering (PubMed:20171176).