V-type proton ATPase subunit H

UniProtKB accession:  P41807

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:8349704, PubMed:27295975). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (PubMed:8349704, PubMed:27295975). This subunit is essential for activity, but not assembly, of the enzyme complex (PubMed:8349704, PubMed:27295975). This subunit is also required for silencing the ATPase activity of V-ATPase when V1 is detached from V0 (PubMed:27295975).