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Deoxyuridine 5'-triphosphate nucleotidohydrolase

UniProtKB accession:  P33317
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Go to UniProtKB:  P33317
UniProtKB description:  Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (PubMed:8223452, PubMed:21548881). Shows a significant activity against dITP, another potentially mutagenic nucleotide (PubMed:21548881).
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