Nuclear polyadenylated RNA-binding protein NAB2

UniProtKB accession:  P32505

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Essential protein that binds to polyadenylated RNA and single-stranded DNA (PubMed:8474438). It may be involved not only in RNA processing but also in transcription regulation. Associates directly with nascent RNA polymerase II transcripts and remain associated during subsequent nuclear RNA processing reactions (Probable). Involved in mRNA poly(A) tail length control and nuclear export (PubMed:11927564, PubMed:11779864). Functions in surveillance and the packaging leading to generation of export-competent mRNPs. Controls both mRNP compaction that facilitates movement through nuclear pore complexes and the length of transcript poly(A) tails (PubMed:19840948, PubMed:22560733).