Centromere DNA-binding protein complex CBF3 subunit A

UniProtKB accession:  P32504

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Acts as a component of the centromere DNA-binding protein complex CBF3, which is essential for chromosome segregation and movement of centromeres along microtubules. CBF3 is required for the recruitment of other kinetochore complexes to CEN DNA. It plays a role in the attachment of chromosomes to the spindle and binds selectively to a highly conserved DNA sequence called CDEIII, found in centromers and in several promoters.