Tegument protein BKRF4

UniProtKB accession:  P30117

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Overcomes the host DNA damage response (DDR) triggered by double-stranded DNA breaks by binding to host histones H2A/H2B, H3/H4 and to cellular chromatin (PubMed:35870648, PubMed:36067323). Can associate with the partially unfolded nucleosomes, promoting the nucleosome disassembly (PubMed:36067323). Interferes with histone ubiquitination and recruitment of repair proteins (PubMed:29743367).