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Protein OPG176

UniProtKB accession:  P26672
Grouped By:  Matching UniProtKB accession
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Go to UniProtKB:  P26672
UniProtKB description:  BCL2-like protein which disrupts the host immune response by inhibiting the TLR4 signaling pathway leading to NF-kappa-B activation. Acts close to the plasma membrane and targets several host TIR-domain containing adapter proteins including MYD88, TIRAP, TRIF and TICAM2. In turn, blocks the host NF-kappa-B and TRIF-mediated IRF3 activation.
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