Vancomycin/teicoplanin A-type resistance protein VanA
UniProtKB accession: P25051
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Go to UniProtKB: P25051
UniProtKB description: Required for high-level resistance to glycopeptide antibiotics. D-Ala--D-Ala ligase of altered specificity which catalyzes ester bond formation between D-Ala and various D-hydroxy acids; produces a peptidoglycan which does not terminate in D-alanine but in D-lactate, thus preventing vancomycin or teicoplanin binding.
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