Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

UniProtKB accession:  P20095

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Involved in pre-mRNA splicing. Is required together with ATP and at least one other factor, for the first cleavage-ligation reaction. Functions as a molecular motor in the activation of the precatalytic spliceosome for the first transesterification reaction of pre-mRNA splicing by hydrolyzing ATP to cause the activation of the spliceosome without the occurrence of splicing. Capable of hydrolyzing nucleoside triphosphates in the presence of single-stranded RNAs such as poly(U).