DNA polymerase delta catalytic subunit

UniProtKB accession:  P15436

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Catalytic component of DNA polymerase delta (DNA polymerase III) which participates in chromosomal DNA replication (PubMed:2670563, PubMed:22119860, PubMed:31488849). Required during synthesis of the lagging DNA strands at the replication fork, binds at/or near replication origins and moves along DNA with the replication fork (PubMed:31488849). Participates in leading strand synthesis during replication initiation and termination (PubMed:31488849). Has 3'-5' proofreading exonuclease activity that corrects errors arising during DNA replication (PubMed:1648480).