Acetyl-CoA acetyltransferase

UniProtKB accession:  P14611

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Catalyzes the condensation of two acetyl-coA units to form acetoacetyl-CoA (PubMed:4198758). Is involved in the biosynthesis of polyhydroxybutyrate (PHB), which is accumulated as an intracellular energy reserve material when cells grow under conditions of nutrient limitation (PubMed:2670936, PubMed:4198758). Also catalyzes the reverse reaction, i.e. the cleavage of acetoacetyl-CoA, and is therefore also involved in the reutilization of PHB (PubMed:4198758, PubMed:25152395).