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Exotoxin A

UniProtKB accession:  P11439
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Go to UniProtKB:  P11439
UniProtKB description:  An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NAD(+)) onto eukaryotic elongation factor 2 (eEF-2) thus arresting protein synthesis (PubMed:2170123, PubMed:18276581). Has an LD(50) of 65 ng/ml against the human lung epithelial cell line C38 (PubMed:21135177).
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