DNA-binding transcriptional repressor ScoC
UniProtKB accession: P11065
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Go to UniProtKB: P11065
UniProtKB description: Negative regulator of protease production and sporulation. Acts by binding directly to the promoter of protease genes (aprE and nprE), and by repressing oligopeptide permease operons (appABCDF and oppABCDF), thereby preventing uptake of oligopeptides required for initiation of sporulation. Acts with SinR as a corepressor of epr expression. Binds to non-m6A-5-methylated 5'-GACGAG-3' sites, tested with scpA; when the target is methylated by DnmA, this repressor no longer binds and transcription is up-regulated (PubMed:32324221).
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