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DNA-guanine transglycosylase

UniProtKB accession:  P0DW33
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Go to UniProtKB:  P0DW33
UniProtKB description:  Part of the dpd cluster involved in the insertion of 7-deazaguanine derivatives in DNA (PubMed:26929322, PubMed:30159947). DpdA may insert 7-cyano-7-deazaguanine (preQ0) into DNA with the help of DpdB (PubMed:30159947). DpdA and dpdB are necessary and sufficient to synthesize 2'-deoxy-7-cyano-7-deazaguanosine (dPreQ0) (PubMed:30159947).
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