Kunitz-type serine protease inhibitor LmKTT-1a

UniProtKB accession:  P0DJ46

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Dual-function toxin that completely inhibits trypsin activity at a molar ratio of 1:1 (Ki=140 nM) and that inhibits mKv1.3/KCNA3 potassium channel currents (1 uM inhibits 50% of currents) (IC(50)=1.58 uM). Shows also weak inhibition on Kv1.1/KCNA1 (1 uM inhibits 25% of currents) and Kv1.2/KCNA2 (1 uM inhibits 25% of currents).