Neurotoxin beta-KTx 14.3

UniProtKB accession:  P0CI42

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UniProtKB description:  Toxin with activity on voltage-gated potassium channels. Moderately and reversibly blocks up to 50% of the activity of Kv7.1/KCNQ1 (tested at 22 uM) (PubMed:36918120). 3D-structure modeling of the KCNQ1-toxin complex shows that the toxin interacts with the channel pore domain (PubMed:36918120). Additionally, shows a very weak effect to block voltage-gated potassium channel Kv1.1/KCNA1 (PubMed:20663230).