5,10-methylenetetrahydrofolate reductase
UniProtKB accession: P0AEZ1
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Go to UniProtKB: P0AEZ1
UniProtKB description: Catalyzes the NADH-dependent reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate (PubMed:9922232). Is required to provide the methyl group necessary for methionine synthetase to convert homocysteine to methionine; the methyl group is given by 5-methyltetrahydrofolate. Can also use NADPH as the reductant, but much less effectively than NADH (PubMed:9922232).
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