O-acetyl-ADP-ribose deacetylase

UniProtKB accession:  P0A8D6

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Deacetylates O-acetyl-ADP ribose to yield ADP-ribose and free acetate (PubMed:21257746, PubMed:26481419). Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation (PubMed:19141481). Overexpression inhibits biofilm formation via an RNase III-independent pathway. This inhibition is RpoS-dependent (PubMed:24267348, PubMed:28582517). Overexpression also results in increased susceptibility to apramycin (PubMed:28034758, PubMed:28582517).