Enterotoxin type A

UniProtKB accession:  P0A0L2

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules (PubMed:2658055, PubMed:12467569). In turn, waves of cellular activation, cytokine production, and migration into the lung tissue and airways occur via alphabeta T-cells (PubMed:23321986). Causes also the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death (Probable).