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Gamma-hemolysin component B

UniProtKB accession:  P0A077
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Go to UniProtKB:  P0A077
UniProtKB description:  Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. Promotes host AMFR-mediated inflammation by mediating 'Lys-27'-linked ubiquitination of TAB3, TAK1-TAB3 complex formation and phosphorylation of TAK1/MAP3K7. In turn, activates host NF-kappa-B signaling pathway.
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