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Intercellular adhesion molecule 1

UniProtKB accession:  P05362
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Go to UniProtKB:  P05362
UniProtKB description:  ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
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