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Non-structural protein 1

UniProtKB accession:  P03502
Grouped By:  Matching UniProtKB accession
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Go to UniProtKB:  P03502
UniProtKB description:  Binds and inhibits the conjugation of the ubiquitin-like G1P2/ISG15 protein to its target proteins. Since G1P2/ISG15 is an early antiviral protein, NS1 may inhibit the host antiviral response. Prevents EIF2AK2/PKR activation, either by binding double strand RNA or by interacting directly with EIF2AK2/PKR. Also binds poly(A) and U6 snRNA.
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