3-hydroxy-3-methylglutaryl-coenzyme A reductase
UniProtKB accession: P00347
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Go to UniProtKB: P00347
UniProtKB description: Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis.
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