DNA-dependent metalloprotease WSS1 homolog 2
UniProtKB accession: O94580
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Go to UniProtKB: O94580
UniProtKB description: Metalloendopeptidase that acts selectively on DNA-binding proteins. DNA is needed to bring the protease and substrates together to enable proteolysis. Involved in the repair of toxic DNA-protein cross-links (DPCs) such as covalently trapped topoisomerase 1 (TOP1) adducts on DNA lesions or DPCs induced by reactive compounds such as formaldehyde.
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