Thioredoxin reductase 1, cytoplasmic

UniProtKB accession:  O89049

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UniProtKB description:  Reduces disulfideprotein thioredoxin (Trx) to its dithiol-containing form. Homodimeric flavoprotein involved in the regulation of cellular redox reactions, growth and differentiation. Contains a selenocysteine residue at the C-terminal active site that is essential for catalysis (PubMed:10849437). Also has reductase activity on hydrogen peroxide (H2O2) (PubMed:10849437).