PRL-1 phosphatase

UniProtKB accession:  O61722

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Probable phosphatase (Probable). Inhibits growth possibly by negatively regulating Src64B-induced growth (PubMed:23577193). Regulates central nervous system circuit formation and stabilization of synapse-dense terminal arbors (PubMed:31048465). In dorsocentral neurons, regulates synaptogenesis in terminal arbors via modulation of the insulin receptor pathway, likely upstream of Akt1, and via reduction of PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) levels (PubMed:31048465). In the nervous system, plays a protective role together with uex in response to olfactory carbon dioxide stimulation (PubMed:31404830).