Apoptosis regulator OPG045
UniProtKB accession: O57173
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Go to UniProtKB: O57173
UniProtKB description: Plays a role in evading host innate immune response by inhibiting host inflammasome activation. Interacts with and inhibits NLR-mediated interleukin-1 beta/IL1B production in infected cells. At the host mitochondria outer membrane, interacts with the BH3 domain of host BAK and prevents BAK from binding active BAX. In turn, host apoptosis is inhibited.
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