Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

UniProtKB accession:  O44074

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Iron-sulfur protein (Ip) subunit of the mitochondrial electron transport chain complex II which, together with the flavoprotein (Fp) subunit forms the catalytic core of the complex (PubMed:10743611, PubMed:8435436, PubMed:7822332, PubMed:17933581, PubMed:2843227, PubMed:12742584). During the free-living egg-larvae stages, which occur in an aerobic environment, complex II acts as a succinate dehydrogenase by transferring electrons from succinate to ubiquinone (PubMed:10743611, PubMed:8435436, PubMed:7822332, PubMed:17933581, PubMed:2843227, PubMed:12742584). During the parasitic larvae and adult stages, which occur in an anaerobic environment, complex II acts as a fumarate reductase by transferring electrons from rhodoquinol to fumarate (PubMed:10743611, PubMed:8435436, PubMed:7822332, PubMed:17933581, PubMed:2843227, PubMed:12742584).