DNA-directed RNA polymerase subunit epsilon

UniProtKB accession:  O31718

Grouped By:  Matching UniProtKB accession

UniProtKB description:  A non-essential component of RNA polymerase (RNAP) (PubMed:6802805, PubMed:18289874, PubMed:21710567, PubMed:25092033). Has a similar structure to bacteriophage T7 protein Gp2 (AC P03704), which is known to bind to RNAP in the DNA binding-cleft. Unlike Gp2 however, this protein does not inhibit transcription initiation (PubMed:25092033). In vitro reconstitution experiments show this subunit is dispensible (PubMed:18289874).