Protein Mdm4
UniProtKB accession: O15151
Grouped By: Matching UniProtKB accession
Group Content:
Go to UniProtKB: O15151
UniProtKB description: Along with MDM2, contributes to TP53 regulation (PubMed:32300648). Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
Group Members:
Release Date:
Structure Features
Sequence Features
Experimental Features
Organisms
Protein Domains
Function
