General transcription and DNA repair factor IIH subunit TFB5

UniProtKB accession:  G0SDQ1

Grouped By:  Matching UniProtKB accession

UniProtKB description:  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.