Endodeoxyribonuclease NucC

UniProtKB accession:  D7Y2H5

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Effector DNase of a CBASS antivirus system (PubMed:31932165, PubMed:31932164). CBASS (cyclic oligonucleotide-based antiphage signaling system) provides immunity against bacteriophage. The CD-NTase protein synthesizes cyclic nucleotides in response to infection; these serve as specific second messenger signals. The signals activate a diverse range of effectors, leading to bacterial cell death and thus abortive phage infection. A type III-C(AAA) CBASS system (PubMed:32839535).