Help  

Mediator of RNA polymerase II transcription subunit 1

UniProtKB accession:  D3ZRN2
Grouped By:  Matching UniProtKB accession
Group Content:  
Go to UniProtKB:  D3ZRN2
UniProtKB description:  Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Group Members:
Release Date:


Structure Features


Sequence Features


Experimental Features


Organisms


Protein Domains


Function