O-ureido-L-serine synthase
UniProtKB accession: D2Z027
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Go to UniProtKB: D2Z027
UniProtKB description: Involved in the biosynthesis of the antibiotic D-cycloserine (DCS), a cyclic structural analog of D-alanine, used as an antitubercular agent (PubMed:20086163). Catalyzes the addition of hydroxyurea on O-acetyl-L-serine (OAS) to yield O-ureido-L-serine. It prefers sulfide as the second substrate, followed by hydroxyurea, L-homocysteine, and thiosulfate (PubMed:26207937).
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