Antifungal protein B

UniProtKB accession:  D0EXD3

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Antifungal protein that acts as an inhibitor of growth of human pathogenic molds and yeasts (PubMed:19683356, PubMed:29379111). Is active against the model organism Neurospora crassa, the opportunistic human pathogens Aspergillus fumigatus, Trichophyton rubrum, and Aspergillus terreus (PubMed:29379111). Provokes a reduction of the incidence of infections caused by Penicillium digitatum and Penicillium italicum in oranges and by Penicillium expansum in apples (PubMed:34199956). Low doses of pafB have self-inhibition activity (PubMed:29379111). Shows also activity against the model yeast Saccaromyces cerevisiae and the opportunistic human pathogen Candida albicans (PubMed:35499318, PubMed:29379111). No antibacterial activity is observed on the Gram-negative Escherichia coli and the Gram-positive Bacillus subtilis (PubMed:29379111). Finally, shows also anti-viral activity in a model of HCoV 229E infected L132 cells (PubMed:29379111).