Velvet complex subunit B

UniProtKB accession:  C8VTS4

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination (PubMed:18556559, PubMed:23049895). The velvet complex acts as a global regulator for secondary metabolite gene expression (PubMed:18556559). Component of the velB-VosA heterodimeric complex that plays a dual role in activating genes associated with spore maturation and repressing certain development-associated genes (PubMed:21152013, PubMed:24391470). The velB-VosA complex binds DNA through the DNA-binding domain of vosA that recognizes an 11-nucleotide consensus sequence 5'-CTGGCCGCGGC-3' consisting of two motifs in the promoters of key developmental regulatory genes (PubMed:24391470). The vosA-velB complex binds to the beta-glucan synthase fksA gene promoter in asexual spores for repression (PubMed:25960370).