diphthine methyl ester synthase
UniProtKB accession: C4LWZ7
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Go to UniProtKB: C4LWZ7
UniProtKB description: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.
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