AA11 family lytic polysaccharide monooxygenase A

UniProtKB accession:  B0XZD3

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UniProtKB description:  Lytic polysaccharide monooxygenase (LMPO) that depolymerizes chitin via the oxidation of scissile beta-(1-4)-glycosidic bonds, yielding C1 or C4 oxidation products (PubMed:34798071). Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate (PubMed:34798071). Has considerable affinity for alpha-chitin and, more so, beta-chitin (PubMed:34798071). Active toward both alpha-chitin and beta-chitin allomorphs and enhances chitin degradation by an endoacting chitinase, in particular for alpha-chitin, and so plays a role in fungal chitin turnover (PubMed:34798071). The catalytic activity increases when supplying reactions with hydrogen peroxide, confirming that it has peroxygenase activity (PubMed:34798071). Does not show activity on phosphoric acid-swollen cellulose (PASC), Avicel, tamarind xyloglucan, birchwood xylan, beechwood xylan, acetyl glucuronoxylan from aspen, ivory nut mannan, acetylated konjac glucomannan, potato starch, heparin, hyaluronic acid, and chitosan (PubMed:34798071).