Zinc chaperone AztD

UniProtKB accession:  A1B2F4

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Acts as a zinc chaperone in the AztABCD zinc transport system (PubMed:26468286, PubMed:32781785, PubMed:30353723, PubMed:31428696). Directly transfers one zinc cation to the solute binding protein AztC; the transfer occurs without the formation of a stable interaction (PubMed:26468286, PubMed:32781785, PubMed:31428696). Binds 3 Zn(2+), two with high affinity and one with low affinity, and transfers only Zn(2+) bound to site 2 to AztC (PubMed:26468286, PubMed:31428696). Likely functions to store zinc in the periplasm and may be important for zinc accumulation in zinc-limited environments (PubMed:32781785).