7UX6

Crystal structure of MfnG, an L- and D-tyrosine O-methyltransferase from the marformycin biosynthesis pathway of Streptomyces drozdowiczii, with SAH bound at 1.35 A resolution (P212121 - form I)

External Resource: Annotation


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APF16864e7ux6A2 A: alpha arraysX: HTHH: HTHT: wingedF: PF16864ECOD (1.6)
APF00891e7ux6A1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: S-adenosyl-L-methionine-dependent methyltransferasesF: PF00891ECOD (1.6)
BPF16864e7ux6B2 A: alpha arraysX: HTHH: HTHT: wingedF: PF16864ECOD (1.6)
BPF00891e7ux6B1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: S-adenosyl-L-methionine-dependent methyltransferasesF: PF00891ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF16864Dimerisation domain (Dimerisation2)Dimerisation domainThis domain, found in methyltransferases, functions as a dimerisation domain [1].Domain
A, B
PF13489Methyltransferase domain (Methyltransf_23)Methyltransferase domainThis family appears to be a methyltransferase domain.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
MfnG - -

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B
IPR031725Acetylserotonin O-methyltransferase, dimerisation domainDomain
A, B
IPR016461O-methyltransferase COMT-typeFamily
A, B
IPR029063S-adenosyl-L-methionine-dependent methyltransferase superfamilyHomologous Superfamily
A, B
IPR036388Winged helix-like DNA-binding domain superfamilyHomologous Superfamily
A, B
IPR036390Winged helix DNA-binding domain superfamilyHomologous Superfamily